More than 900 new homes - around half of which would be affordable or suitable for families - have been given the go-ahead for part of the 2012 Olympic Park.
The new homes are part of London Legacy Development Corporation's (LLDC) development plan to transform Pudding Mill Lane, Stratford, into a new commercial and residential neighbourhood.
A total of 45 per cent of the new homes would be affordable and 51 per cent suitable for families.
Rosanna Lawes, executive director of development at LLDC, said: "The planning consent marks another major milestone in the delivery of much needed homes and workspace on the Park.
"There will be significant levels of genuinely affordable and family-sized homes as well as significant workspace to support the creation of jobs."
The outline application plan includes around 948 homes. A total of 45 per cent of these homes will be affordable, of which 30 per cent will be low-cost rented housing.
Some 51 per cent of homes will be family-sized and there will be 40 homes for older people.
The Pudding Mill Lane site, next to the DLR station, will be designed by Gort Scott, 5th Studio and Jonathan Cook Landscape Architects.
Alan Worn, associate at Gort Scott, said: "Pudding Mill Lane has a rich history with a character shaped by its waterways and industrial heritage.
"We want to bring that character through and are therefore delighted that our masterplan is underpinned by high quality design standards and a rigorous design code that sets this out.
"Ten years after the opening of the Queen Elizabeth Olympic Park, we are seeing the final piece of the jigsaw beginning to fall into place, and we are very proud to be a part of that legacy."
The development will also see 52,000sq m of employment and community space, two new riverside parks and a new urban square at Pudding Mill DLR station.
LLDC said building work is due to start on site in 2026 and be completed by 2033
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